West Nile Virus Viremia in Eastern Chipmunks (Tamias striatus) Sufficient for Infecting Different Mosquitoes

dc.contributor.author Platt, Kenneth
dc.contributor.author Tucker, Bradley
dc.contributor.author Halbur, Patrick
dc.contributor.author Tiawsirisup, Sonthaya
dc.contributor.author Blitvich, Bradley
dc.contributor.author Fabiosa, Flor
dc.contributor.author Bartholomay, Lyric
dc.contributor.author Rowley, Wayne
dc.contributor.department Entomology
dc.date 2018-02-14T14:46:32.000
dc.date.accessioned 2020-06-30T02:21:58Z
dc.date.available 2020-06-30T02:21:58Z
dc.date.copyright Mon Jan 01 00:00:00 UTC 2007
dc.date.embargo 2014-09-10
dc.date.issued 2007-01-01
dc.description.abstract <p>In eastern chipmunks (<em>Tamias striatus</em>) inoculated intramuscularly with 101.5 to 105.7 PFU of West Nile virus (WNV), serum titers developed sufficient to infect <em>Aedes triseriatus</em> (Say), <em>Ae. vexans</em> (Meigen), and<em>Culex pipiens</em> (L.). Mean titers (95% confidence interval) of 8 chipmunks were 103.9(3.3–4.5), 106.7(6.4–7.0), and 105.8(4.1–7.5) PFU/mL on days 1–3 postinoculation (p.i.) and 105.8 PFU/mL in 1 chipmunk on day 4 p.i. Mean estimated days that WNV titers were >104.8 and >105.6 were 1.7 (1.1–2.3) and 1.4 (1.0–1.6). The longest period of viremia >104.8 PFU/mL was 3–4 days. WNV antigen was detected in the small intestine of 2 chipmunks and the kidneys of 4 chipmunks by immunohistochemistry. WNV also was detected in urine, saliva, and feces of some chipmunks. These data suggest chipmunks might play a role in enzootic WNV cycles and be an amplifying host for mosquitoes that could infect humans.</p>
dc.description.comments <p>This article is from <em>Emerging Infectious Diseases</em> 13 (2007): 831, doi:<a href="http://dx.doi.org/10.3201%2Feid1306.061008" target="_blank">10.3201/eid1306.061008</a></p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/ent_pubs/149/
dc.identifier.articleid 1157
dc.identifier.contextkey 6102190
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ent_pubs/149
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/23751
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/ent_pubs/149/2007_Bartholomay_WestNile.pdf|||Fri Jan 14 20:28:15 UTC 2022
dc.source.uri 10.3201/eid1306.061008
dc.subject.disciplines Entomology
dc.subject.disciplines Virology
dc.subject.disciplines Virus Diseases
dc.subject.disciplines Zoology
dc.subject.keywords West Nile virus
dc.subject.keywords chipmunks
dc.subject.keywords Aedes triseriatus
dc.subject.keywords Aedes vexans
dc.subject.keywords Culex pipiens
dc.subject.keywords research
dc.title West Nile Virus Viremia in Eastern Chipmunks (Tamias striatus) Sufficient for Infecting Different Mosquitoes
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isOrgUnitOfPublication f47c8cad-50be-4fb0-8870-902ff536748c
File
Original bundle
Now showing 1 - 1 of 1
Name:
2007_Bartholomay_WestNile.pdf
Size:
333.76 KB
Format:
Adobe Portable Document Format
Description:
Collections