Divergent Approach to Flavones and Aurones via Dihaloacrylic Acids. Unexpected Dependence on the Halogen Atom
The reaction of phenols with 7a led to the synthesis of aurones, while the reaction of phenols with 7b led to the synthesis of flavones.
Reprinted (adapted) with permission from Organic Letters, 12(22); 5278-5280. Doi: 10.1021/ol1023294. Copyright 2010 American Chemical Society.