Assessment of risk of insect-resistant transgenic crops to nontarget arthropods

Date
2008-02-01
Authors
Romeis, Jörg
Hellmich, Richard
Bartsch, Detlef
Bigler, Franz
Candolfi, Marco
Gielkens, Marco
Hartley, Susan
Hellmich, Richard
Huesing, Joseph
Jepson, Paul
Layton, Raymond
Quemada, Hector
Raybould, Alan
Rose, Robyn
Schiemann, Joachim
Sears, Mark
Shelton, Anthony
Sweet, Jeremy
Vaituzis, Zigfridas
Wolt, Jeffrey
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Entomology
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Entomology
Abstract

An international initiative is developing a scientifically rigorous approach to evaluate the potential risks to nontarget arthropods (NTAs) posed by insect-resistant, genetically modified (IRGM) crops. It adapts the tiered approach to risk assessment that is used internationally within regulatory toxicology and environmental sciences. The approach focuses on the formulation and testing of clearly stated risk hypotheses, making maximum use of available data and using formal decision guidelines to progress between testing stages (or tiers). It is intended to provide guidance to regulatory agencies that are currently developing their own NTA risk assessment guidelines for IRGM crops and to help harmonize regulatory requirements between different countries and different regions of the world.

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This article is from Nature Biotechnology; 26 (2008); 203-208; doi:10.1038/nbt1381

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