The objective of this study was to evaluate Priaxor and Headline fungicides on two different soybean varieties. Past studies have shown yield benefit from fungicide application in the absence of foliar leaf disease. Pioneer 92Y51 and Kruger K2-1901 were planted May 14 at 156,00 seeds/acre. The fungicide treatments were 6.0 oz/acre of Headline or 4.0 oz/acre of Priaxor plus 4.0 oz/acre NIS at 13.9 GPA on July 23 at the R3 stage of development. Plot size was eight, 30-in. rows by 75 ft in length. The center six rows were harvested for yield data. The plot was harvested on September 18, 2012.