The use of a Salmonella Typhimurium live vaccine to control Salmonella Typhimurium in fattening pigs in field and effects on serological surveillance
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The SafePork conference series began in 1996 to bring together international researchers, industry, and government agencies to discuss current Salmonella research and identify research needs pertaining to both pig and pork production. In subsequent years topics of research presented at these conferences expanded to include other chemical and biological hazards to pig and pork production.
This field study was designed to evaluate the use of a live-attenuated Salmonella Typh1murium vaccine in pigs in respect of efficacy agamst S. Typhimurium at time of slaughter and the effect on serological herd monitoring using a commercial mixed LPS-ELISA. About 1289 slaughtered pigs (805 of non vaccinated groups and 484 of vaccinated groups) were investigated by bacteriological and serological examination (1149 pigs). The study showed the efficacy of an oral vaccination with a live-attenuated Salmonella Typhimunum vaccme in reducmg the number of Salmonella carrying pigs at slaughter without a detectable interference with the serological monitoring of Salmonella (using a cut off at 40% OD level).