Assessment of the diagnostic accuracy of three commercial ELISAs for the detection of antibodies against Salmonella spp in pigs through Bayesian methods
Assessment of the diagnostic accuracy of three commercial ELISAs for the detection of antibodies against Salmonella spp in pigs through Bayesian methods
Date
2009-01-01
Authors
Mainar-Jaime, R.
Vico, J.
Engel, B.
Buist, W.
Vico, J.
Engel, B.
Buist, W.
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Abstract
The diagnostic accuracy of three ELISA tests (Herdcheck® Swine Salmonella, SALMOTYPE® Pig Screen, and PrioCHECK® Salmonella) was analysed. A low correlation between herd prevalence according to bacteriology and herd seroprevalence using the three ELISAs was found. Their estimated sensitivity (Se) and specificity (Sp) using a Bayesian approach was variable, with Herdcheck® Swine Salmonella showing the best overall accuracy (Se= 0.88; Sp= 0.74). All of the ELISAs overlooked an important proportion of Salmonella-infected pigs.