TMS Effect on Growth Rate of N27 Neuron Cells
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The Department of Electrical and Computer Engineering (ECpE) contains two focuses. The focus on Electrical Engineering teaches students in the fields of control systems, electromagnetics and non-destructive evaluation, microelectronics, electric power & energy systems, and the like. The Computer Engineering focus teaches in the fields of software systems, embedded systems, networking, information security, computer architecture, etc.
History
The Department of Electrical Engineering was formed in 1909 from the division of the Department of Physics and Electrical Engineering. In 1985 its name changed to Department of Electrical Engineering and Computer Engineering. In 1995 it became the Department of Electrical and Computer Engineering.
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1909-present
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- Department of Electrical Engineering (1909-1985)
- Department of Electrical Engineering and Computer Engineering (1985-1995)
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- College of Engineering (parent college)
- Department of Physics and Electrical Engineering (predecessor)
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The Symposium provides undergraduates from all academic disciplines with an opportunity to share their research with the university community and other guests through conference-style oral presentations. The Symposium represents part of a larger effort of Iowa State University to enhance, support, and celebrate undergraduate research activity.
Though coordinated by the University Honors Program, all undergraduate students are eligible and encouraged to participate in the Symposium. Undergraduates conducting research but not yet ready to present their work are encouraged to attend the Symposium to learn about the presentation process and students not currently involved in research are encouraged to attend the Symposium to learn about the broad range of undergraduate research activities that are taking place at ISU.
The first Symposium was held in April 2007. The 39 students who presented research and their mentors collectively represented all of ISU's Colleges: Agriculture and Life Sciences, Business, Design, Engineering, Human Sciences, Liberal Arts and Sciences, Veterinary Medicine, and the Graduate College. The event has grown to regularly include more than 100 students presenting on topics that span the broad range of disciplines studied at ISU.
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Abstract
Transcranial magnetic stimulation (TMS) is a non-invasive method for modulating neurons in the brain. The technique has been investigated for a variety of diagnostic and therapeutic applications for neurological disorders such as Parkinson's disease and Post-Traumatic Stress Disorder (PTSD). TMS treatment has been approved by US Food and Drug Administration for the treatment of depression; however, the effect of TMS on individual neurons is least understood. We first carried out the experiment to investigate the effect of magnetic field on the growth rate of neuronal cells. N27 cell is one type of dopaminergic neuronal cells from the brain of mice. We first cultured the cells in the incubator. After that, we used the air-cooled double coil to treat them at specific growing period with short pulses of time varying magnetic field. Each treatment was 30 minutes long. We counted the number of cells 24 hours after the TMS treatment to ensure enough time was given to see the effect on the growth of N27 cells. After using three different cell counting methods, we found the grow rate of N27 cells increased with upward oriented magnetic field treatment while it decreased with downward oriented magnetic field treatment.