Analyzing Chromosomes, Ion Channels and Novel Nucleic Acid Structures by AFM
Date
1994
Authors
Henderson, Eric
Ambrosio, Linda
Mosher, Curtis
Jondle, Daniel
Stanley, Elis
Haydon, Philip
Marsh, Thomas
Vesenka, James
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Henderson, Eric
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Zoology and Genetics
Abstract
The atomic force microscope (AFM) is proving to be a powerful tool for analysis of biological samples. We provide three examples of the application of AFM to the study of biological questions. First, polytene chromosomes from Drosophila are imaged and manipulated by the AFM. Second, the localization of calcium channels on the release face of a nerve terminal is described. Finally, analyses of a new form of DNA, the G-wire, is presented. These examples illustrate the wide variety of biological questions to which AFM can contribute.
Comments
This is a proceeding from NATO Advanced Research Workshop: "Scanning Probe Microscopies and Molecular Materials" (1994): 1.