Impact of Linker Engineering on the Catalytic Activity of Metal–Organic Frameworks Containing Pd(II)–Bipyridine Complexes
Van Zeeland, Ryan
A series of mixed-linker bipyridyl metal–organic framework (MOF)-supported palladium(II) catalysts were used to elucidate the electronic and steric effects of linker substitution on the activity of these catalysts in the context of Suzuki–Miyaura cross-coupling reactions. m-6,6′-Me2bpy-MOF-PdCl2 exhibited 110- and 496-fold enhancements in activity compared to nonfunctionalized m-bpy-MOF-PdCl2 and m-4,4′-Me2bpy-MOF-PdCl2, respectively. This result clearly demonstrates that the stereoelectronic properties of metal-binding linker units are critical to the activity of single-site organometallic catalysts in MOFs and highlights the importance of linker engineering in the design and development of efficient MOF catalysts.
This document is the Accepted Manuscript version of a Published Work that appeared in final form as Li, Xinle, Ryan Van Zeeland, Raghu V. Maligal-Ganesh, Yuchen Pei, Gregory Power, Levi Stanley, and Wenyu Huang. "Impact of linker engineering on the catalytic activity of metal–organic frameworks containing Pd (II)–bipyridine complexes." ACS Catalysis 6, no. 9 (2016): 6324-6328, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see DOI: 10.1021/acscatal.6b01753. Posted with permission.