The purpose of this study is to investigate potential regional differences in the supply response of crop producers to alternative market and government policy incentives. To accomplish this task, a set of acreage response functions are specified and estimated for 8 principal field crops (spring wheat, winter wheat, corn, sorghum, oats, barley, soybeans, and cotton) produced in 11 spatial regions of the United States (Appalachia, Corn Belt, Delta States, Lake States, Northeast, Northern Plains, Northwest, Southeast, Southern Plains, Southwest, and Western Plains). Variables in the functions include those related to expected per-acre gross returns from crop production, the impact of government policy programs (especially, loan rates, target prices, diversion payments, and allotments), and the effects of risk and uncertainty upon acreage response. Important elasticities are determined for each crop and region.