Post-weaning Failure to Thrive in Pigs is Associated with Increased Organ Weights and Possible Anemia, but not Changes in Intestinal Function Jones, Cassandra Patience, John Patience, John Gabler, Nicholas 2018-08-25T18:52:19.000 2020-06-29T23:34:06Z 2020-06-29T23:34:06Z Sun Jan 01 00:00:00 UTC 2012 2012-01-01
dc.description.abstract <p>A total of 96 weanling barrows were utilized in a 27 d experiment to determine the effects of post-weaning failure to thrive (PFTS) on organ weight, blood chemistry, and small intestine physiology and function. Thirty-two pigs from each of the lightest, median, and heaviest weight categories at weaning were placed in individual metabolism cages and allowed ad libitum access to water and a common nursery diet. After a 5 d acclimation period, growth rate was evaluated for 27 d. Pigs with ADG that were below two standard deviations from the mean were termed pigs with PFTS (n = 4). All other pigs were considered normal contemporaries. After the 27 d experiment, pigs were fasted overnight and humanely euthanized. Organs were emptied of digesta and weighed, blood was collected for analysis in a complete blood panel and white blood cell differential, and ileal samples taken for morphology and absorptive capacity analyses. Pigs with PFTS had increased (P < 0.02) stomach, intestine, kidney, and liver weights relative to body size. Additionally, PFTS pigs had decreased (P < 0.05) hemoglobin hematocrit, albumin, sodium, and anion gap concentrations, suggesting either anemia or increased dehydration compared to normal pigs. Finally, PFTS was associated with increased ileal villous crypt depth (P < 0.0001), but not with villous height or differences in absorptive capacity of various glucose or amino acids. These data suggest that pigs with PFTS may have a higher maintenance cost due to increased organ weight and a possible anemia or imbalance of blood chemistry. However, differences in post-weaning performance do not appear to affect small intestine function.</p>
dc.identifier archive/
dc.identifier.articleid 1772
dc.identifier.contextkey 3410204
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_air/vol658/iss1/66
dc.language.iso en
dc.relation.ispartofseries Animal Science Research Reports
dc.source.bitstream archive/|||Sat Jan 15 01:24:57 UTC 2022
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.keywords ASL R2734
dc.title Post-weaning Failure to Thrive in Pigs is Associated with Increased Organ Weights and Possible Anemia, but not Changes in Intestinal Function
dc.type article
dc.type.genre swine
dspace.entity.type Publication
relation.isAuthorOfPublication 5888d61a-1b3d-48c9-ab84-deb63aa3a43c
relation.isJournalIssueOfPublication 6dc63976-6a4a-4b75-a79f-e40937b79e61
relation.isSeriesOfPublication 7f3839b7-b833-4418-a6fa-adda2b23950a
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