Post-weaning Failure to Thrive in Pigs is Associated with Increased Organ Weights and Possible Anemia, but not Changes in Intestinal Function
dc.contributor.author | Jones, Cassandra | |
dc.contributor.author | Patience, John | |
dc.contributor.author | Gabler, Nicholas | |
dc.date | 2018-08-25T18:52:19.000 | |
dc.date.accessioned | 2020-06-29T23:34:06Z | |
dc.date.available | 2020-06-29T23:34:06Z | |
dc.date.copyright | Sun Jan 01 00:00:00 UTC 2012 | |
dc.date.issued | 2012-01-01 | |
dc.description.abstract | <p>A total of 96 weanling barrows were utilized in a 27 d experiment to determine the effects of post-weaning failure to thrive (PFTS) on organ weight, blood chemistry, and small intestine physiology and function. Thirty-two pigs from each of the lightest, median, and heaviest weight categories at weaning were placed in individual metabolism cages and allowed ad libitum access to water and a common nursery diet. After a 5 d acclimation period, growth rate was evaluated for 27 d. Pigs with ADG that were below two standard deviations from the mean were termed pigs with PFTS (n = 4). All other pigs were considered normal contemporaries. After the 27 d experiment, pigs were fasted overnight and humanely euthanized. Organs were emptied of digesta and weighed, blood was collected for analysis in a complete blood panel and white blood cell differential, and ileal samples taken for morphology and absorptive capacity analyses. Pigs with PFTS had increased (P < 0.02) stomach, intestine, kidney, and liver weights relative to body size. Additionally, PFTS pigs had decreased (P < 0.05) hemoglobin hematocrit, albumin, sodium, and anion gap concentrations, suggesting either anemia or increased dehydration compared to normal pigs. Finally, PFTS was associated with increased ileal villous crypt depth (P < 0.0001), but not with villous height or differences in absorptive capacity of various glucose or amino acids. These data suggest that pigs with PFTS may have a higher maintenance cost due to increased organ weight and a possible anemia or imbalance of blood chemistry. However, differences in post-weaning performance do not appear to affect small intestine function.</p> | |
dc.identifier | archive/lib.dr.iastate.edu/ans_air/vol658/iss1/66/ | |
dc.identifier.articleid | 1772 | |
dc.identifier.contextkey | 3410204 | |
dc.identifier.doi | https://doi.org/10.31274/ans_air-180814-978 | |
dc.identifier.s3bucket | isulib-bepress-aws-west | |
dc.identifier.submissionpath | ans_air/vol658/iss1/66 | |
dc.identifier.uri | https://dr.lib.iastate.edu/handle/20.500.12876/8906 | |
dc.language.iso | en | |
dc.relation.ispartofseries | Animal Science Research Reports | |
dc.relation.ispartofseries | ASL R2734 | |
dc.source.bitstream | archive/lib.dr.iastate.edu/ans_air/vol658/iss1/66/R2734.pdf|||Sat Jan 15 01:24:57 UTC 2022 | |
dc.subject.disciplines | Agriculture | |
dc.subject.disciplines | Animal Sciences | |
dc.subject.keywords | ASL R2734 | |
dc.title | Post-weaning Failure to Thrive in Pigs is Associated with Increased Organ Weights and Possible Anemia, but not Changes in Intestinal Function | |
dc.type | article | |
dc.type.genre | swine | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 5888d61a-1b3d-48c9-ab84-deb63aa3a43c | |
relation.isJournalIssueOfPublication | 6dc63976-6a4a-4b75-a79f-e40937b79e61 | |
relation.isSeriesOfPublication | 7f3839b7-b833-4418-a6fa-adda2b23950a |
File
Original bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- R2734.pdf
- Size:
- 73.25 KB
- Format:
- Adobe Portable Document Format
- Description: