Advances in Campylobacter biology and implications for biotechnological applications Jeon, Byeonghwa Muraoka, Wayne Zhang, Qijing Zhang, Qijing
dc.contributor.department Veterinary Microbiology and Preventive Medicine 2018-02-18T23:07:07.000 2020-07-07T05:14:36Z 2020-07-07T05:14:36Z 2010-05-01
dc.description.abstract <p><h2> </h2></p> <p>Campylobacter jejuni is a major foodborne pathogen of animal origin and a leading cause of bacterial gastroenteritis in humans. During the past decade, especially since the publication of the first C. jejuni genome sequence, major advances have been made in understanding the pathobiology and physiology of this organism. It is apparent that C. jejuni utilizes sophisticated mechanisms for effective colonization of the intestinal tracts in various animal species. Although Campylobacter is fragile in the environment and requires fastidious growth conditions, it exhibits great flexibility in the adaptation to various habitats including the gastrointestinal tract. This high adaptability is attributable to its genetically, metabolically and phenotypically diverse population structure and its ability to change in response to various challenges. Unlike other enteric pathogens, such as Escherichia coli and Salmonella, Campylobacter is unable to utilize exogenous glucose and mainly depends on the catabolism of amino acids as a carbon source. Campylobacter proves highly mutable in response to antibiotic treatments and possesses eukaryote-like dual protein glycosylation systems, which modify flagella and other surface proteins with specific sugar structures. In this review we will summarize the distinct biological traits of Campylobacter and discuss the potential biotechnological approaches that can be developed to control this enteric pathogen.</p>
dc.description.comments <p>This article is published as Jeon, Byeonghwa, Wayne T. Muraoka, and Qijing Zhang. "Advances in Campylobacter biology and implications for biotechnological applications." Microbial biotechnology 3, no. 3 (2010): 242-258. doi: <a href="" target="_blank" title="Advances in Campylobacter biology and implications for biotechnological applications">10.1111/j.1751-7915.2009.00118.x.</a> Posted with permission.</p>
dc.format.mimetype application/pdf
dc.identifier archive/
dc.identifier.articleid 1147
dc.identifier.contextkey 10786465
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath vmpm_pubs/148
dc.language.iso en
dc.source.bitstream archive/|||Fri Jan 14 20:26:46 UTC 2022
dc.source.uri 10.1111/j.1751-7915.2009.00118.x
dc.subject.disciplines Genetics and Genomics
dc.subject.disciplines Veterinary Microbiology and Immunobiology
dc.subject.disciplines Veterinary Pathology and Pathobiology
dc.subject.disciplines Veterinary Preventive Medicine, Epidemiology, and Public Health
dc.title Advances in Campylobacter biology and implications for biotechnological applications
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 1c6a5dfc-c604-457f-85be-122910db782e
relation.isOrgUnitOfPublication 16f8e472-b1cd-4d8f-b016-09e96dbc4d83
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
521.79 KB
Adobe Portable Document Format