Effects of Dietary Macronutrients on Appetite-Related Hormones in Blood on Body Composition of Lean and Obese Rats

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dc.contributor.author Bohan, Michelle
dc.contributor.author Anderson, Lloyd
dc.contributor.author Trenkle, Allen
dc.contributor.author Beitz, Donald
dc.date 2018-08-25T22:28:09.000
dc.date.accessioned 2020-06-29T23:29:42Z
dc.date.available 2020-06-29T23:29:42Z
dc.date.copyright Sun Jan 01 00:00:00 UTC 2006
dc.date.issued 2006-01-01
dc.description.abstract <p>Investigating the role of appetite-related hormones on energy balance and body composition when varying diets are consumed could provide insight into the etiology of obesity. Fifty-three adult male Sprague Dawley and 30 adult male Zucker Fatty rats were assigned randomly to one of five diets: Control, 75% control, American Heart Association (AHA), Atkins, or high fat (HF). Diets were fed for five weeks. Weekly plasma samples were collected and analyzed for ghrelin, leptin, insulin, and adiponectin. Terminal plasma samples were analyzed for ghrelin, leptin, insulin, glucagon, oxyntomodulin, adiponectin, and blood metabolites. Our results indicate that macronutrient composition of the diet influences appetite-related hormones differently in genetically divergent rats. For example, glucagon concentration was higher in obese rats fed the Atkins diet in comparison to obese rats fed the HF and 75% control diets (P<0.05) and tended to be higher in obese rats fed the Atkins diet in comparison with rats fed the AHA and control diets (0.06</p>
dc.identifier archive/lib.dr.iastate.edu/ans_air/vol652/iss1/22/
dc.identifier.articleid 1153
dc.identifier.contextkey 3311596
dc.identifier.doi https://doi.org/10.31274/ans_air-180814-908
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_air/vol652/iss1/22
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/8283
dc.language.iso en
dc.relation.ispartofseries Animal Science Research Reports
dc.relation.ispartofseries ASL R2081
dc.source.bitstream archive/lib.dr.iastate.edu/ans_air/vol652/iss1/22/R2081.pdf|||Fri Jan 14 22:39:45 UTC 2022
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.keywords ASL R2081
dc.title Effects of Dietary Macronutrients on Appetite-Related Hormones in Blood on Body Composition of Lean and Obese Rats
dc.type article
dc.type.genre companion_animal
dspace.entity.type Publication
relation.isJournalIssueOfPublication 19a7d362-cc4b-4a86-ae7b-d8638c6352d4
relation.isSeriesOfPublication 7f3839b7-b833-4418-a6fa-adda2b23950a
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