Sound research study of anaplasmosis in cattle has long been conducted in hopes of discovering adequate control measures. The investigators have been numerous, have made their studies in various parts of the world where the disease occurs, under well controlled experimental conditions and under local field conditions. The approaches to solving existing problems have been directed toward phases of investigation, including both those afforded by clinical cases and by recovered carrier cases. In spite of the thoroughness exercised and the well planned investigational procedures followed, experimental results have failed to provide adequate practical control measures.