Streptococcus suis is a major pathogen in the pig industry, associated with a wide variety of pigs diseases, such as meningitis, arthritis, bronchopneumonia, endocarditis, polyserositis and septicaemia. In addition, it is a zoonotic agent causing severe infections in people related with infected pigs or pork-derived products. The control of the disease is based on the antimicrobial therapy and sanitary measures, since there are not available commercial vaccines yet.