The effectiveness of polypeptides from phosvitin and eggshell membrane in enhancing the bioavailability of eggshell powder calcium and its accumulation in bones
Date
2022-11-26
Authors
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier Ltd.
Abstract
The low-calcium-specific pathogen-free C57BL/6 (SPF–C57BL/6) mice were used to explore the effectiveness of phosvitin phosphopeptides (PPPs) and eggshell membrane peptides (EMPs) in improving the intestinal calcium absorption and promoting bone deposition of eggshell calcium (ESCa). Intake of ESCa + PPPs + EMPs significantly down regulated the abnormal elevation of serum alkaline phosphatase (ALP) induced by calcium deficiency. The CaCO3 group had lower calcium absorption rate (34.34%) and femur bone mineral density (BMD) (0.13 g/cm3), while the ESCa + PPPs + EMPs treatment significantly improved calcium absorption rate (55.01%) and femur BMD (0.15 g/cm3). The three-dimensional reconstruction images of mice femur showed that the ESCa + PPPs + EMPs group had a more complete, compact, and thicker trabecular structure than the low-calcium, CaCO3, and ESCa groups. These results indicated that the ESCa is a low-cost alternative calcium supplement to achieve adequate calcium intake, and the presence of polypeptides, such as PPPs and EMPs, is more beneficial to calcium absorption and deposition than the ESCa.
Series Number
Journal Issue
Is Version Of
Versions
Series
Academic or Administrative Unit
Type
article
Comments
This is a manuscript of an article published as Liu, Wei, Cuie Tang, Zhaoxia Cai, Yongguo Jin, Dong Uk Ahn, and Huang Xi. "The effectiveness of polypeptides from phosvitin and eggshell membrane in enhancing the bioavailability of eggshell powder calcium and its accumulation in bones." Food Bioscience (2022): 102257. doi:10.1016/j.fbio.2022.102257. Posted with permission.
This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
This manuscript is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.