Plasmodium falciparum protein export and erythrocyte remodeling in blood-stage malaria infections

dc.contributor.author Peltier, Tanner
dc.contributor.department Biomedical Sciences
dc.contributor.majorProfessor Joshua Beck
dc.date 2021-06-02T14:54:21.000
dc.date.accessioned 2021-08-14T03:34:33Z
dc.date.available 2021-08-14T03:34:33Z
dc.date.copyright Fri Jan 01 00:00:00 UTC 2021
dc.date.embargo 2021-04-19
dc.date.issued 2021-01-01
dc.description.abstract <p>Malaria is a vector-borne disease caused by several unicellular Plasmodium species. Plasmodium are parasitic eukaryotic protozoans within the apicomplexan phylum named for an apical complex of secretory organelles and cytoskeletal components critical for host cell invasion. Infections are deadliest in children under five years of age and pregnant women. Here, we focus on the life cycle of Plasmodium falciparum and the molecular remodeling capabilities implemented against human erythrocytes. These changes can complicate Malaria infections and reach the microvasculature of the brain leading to death in the human host. Millions of Malaria infections occur each year and researching Plasmodium falciparum erythrocyte remodeling may uncover new mitigation efforts. This paper will review research topics covering P. falciparum and the mechanisms used to adapt the erythrocyte to its own needs.</p>
dc.format.mimetype PDF
dc.identifier archive/lib.dr.iastate.edu/creativecomponents/780/
dc.identifier.articleid 1829
dc.identifier.contextkey 22552574
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath creativecomponents/780
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/avVOQV7r
dc.source.bitstream archive/lib.dr.iastate.edu/creativecomponents/780/Plasmodium_falciparum_protein_export_and_erythrocyte_remodeling_in_blood_stage_malaria_infections.pdf|||Sat Jan 15 01:54:32 UTC 2022
dc.subject.disciplines Parasitology
dc.subject.keywords Parasitology
dc.subject.keywords Malaria
dc.subject.keywords erythrocyte
dc.subject.keywords protein export
dc.title Plasmodium falciparum protein export and erythrocyte remodeling in blood-stage malaria infections
dc.type article
dc.type.genre creativecomponent
dspace.entity.type Publication
relation.isOrgUnitOfPublication 184db3f2-d93f-4571-8ad7-07c8a9e6a5c9
thesis.degree.discipline Biomedical Sciences
thesis.degree.level creativecomponent
File
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Plasmodium_falciparum_protein_export_and_erythrocyte_remodeling_in_blood_stage_malaria_infections.pdf
Size:
188.27 KB
Format:
Adobe Portable Document Format
Description: