Phosphorylated Perilipin Abundances Associated with Energy Mobilization in Lactating Dairy Cows

dc.contributor.author Elkins, Dawn
dc.contributor.author Spurlock, Diane
dc.date 2018-08-25T20:55:09.000
dc.date.accessioned 2020-06-29T23:31:59Z
dc.date.available 2020-06-29T23:31:59Z
dc.date.copyright Thu Jan 01 00:00:00 UTC 2009
dc.date.issued 2009-01-01
dc.description.abstract <p>Perilipin, adipose triglyceride lipase (ATGL) and comparative gene identity-58 (CGI-58) are proteins recently associated with energy mobilization from adipose tissue of rodents and humans. Relative protein abundances were measured in 11 early (5-14 DIM) and 9 mid (176-206 DIM) lactation cows. Early lactation cows were mobilizing energy compared to mid lactation cows. Phosphorylation of perilipin was increased in early compared to mid lactation cows, and significantly associated with lipid breakdown. ATGL was significantly increased in mid compared to early lactation, and CGI-58 was similar between stages of lactation. Neither ATGL nor CGI-58 was correlated with lipid breakdown. These results identify perilipin and ATGL as novel proteins involved in the regulation of lipid mobilization throughout lactation.</p>
dc.identifier archive/lib.dr.iastate.edu/ans_air/vol655/iss1/54/
dc.identifier.articleid 1471
dc.identifier.contextkey 3390303
dc.identifier.doi https://doi.org/10.31274/ans_air-180814-2
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_air/vol655/iss1/54
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/8606
dc.language.iso en
dc.relation.ispartofseries Animal Science Research Reports
dc.relation.ispartofseries ASL R2431
dc.source.bitstream archive/lib.dr.iastate.edu/ans_air/vol655/iss1/54/R2431.pdf|||Sat Jan 15 00:52:28 UTC 2022
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.disciplines Dairy Science
dc.subject.keywords ASL R2431
dc.title Phosphorylated Perilipin Abundances Associated with Energy Mobilization in Lactating Dairy Cows
dc.type article
dc.type.genre dairy
dspace.entity.type Publication
relation.isJournalIssueOfPublication 3d9dfb75-1750-45f7-a559-dc2c94d08a2e
relation.isSeriesOfPublication 7f3839b7-b833-4418-a6fa-adda2b23950a
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