Preparation and characterization of novel eggshell membrane-chitosan blend films for potential wound-care dressing: From waste to medicinal products

dc.contributor.author Li, Xiaoyun
dc.contributor.author Ma, Meihu
dc.contributor.author Ahn, Dong
dc.contributor.author Ahn, Dong Uk
dc.contributor.author Huang, Xi
dc.contributor.department Animal Science
dc.date 2021-06-08T20:48:54.000
dc.date.accessioned 2021-08-14T02:09:59Z
dc.date.available 2021-08-14T02:09:59Z
dc.date.copyright Mon Jan 01 00:00:00 UTC 2018
dc.date.issued 2019-02-15
dc.description.abstract <p>A series of different eggshell membrane (ESM) and chitosan (CS) blend films (ESM/CS) were prepared for wound-care dressing. The appearance, transparency and microstructure of the films were characterized. Several wound care-related properties such as the film integrity in solution, pH, protein (BSA) and wound fluid absorption capacity as well as the antibacterial property of ESM/CS films were evaluated. The blend films were more stable than CS film after 95 hours of incubation in solution. The integrity of the blend films improved significantly at the cost of a small insignificant decrease in wound fluid absorption capacity. Besides, the blend films provided an acidic environment (pH = 5.86) for wound healing. The swelling properties of ESM contributed significantly to the increase of BSA absorption capacity of the blend films (from 46.57 mg/g of CS film to 61.07 mg/g of blend film) and helped absorb more nutrients to promote the proliferation and migration of fibroblasts. Addition of CS to ESM also enhanced the antibacterial activity of the films significantly. The results indicated that the EMS/CS blend films with 0.01 g ESM/mL CS solution showed the highest high potential to be used as a wound-care dressing for humans as well as animals.</p>
dc.description.comments <p>This is a manuscript of an article published as Li, Xiaoyun, Meihu Ma, Dong Uk Ahn, and Xi Huang. "Preparation and characterization of novel eggshell membrane-chitosan blend films for potential wound-care dressing: From waste to medicinal products." <em>International journal of biological macromolecules</em> 123 (2019): 477-484. doi:<a href="https://doi.org/10.1016/j.ijbiomac.2018.10.215" target="_blank" title="Persistent link using digital object identifier">10.1016/j.ijbiomac.2018.10.215</a>. Posted with permission.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/ans_pubs/938/
dc.identifier.articleid 1935
dc.identifier.contextkey 23257521
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_pubs/938
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/EzR2Q5Dz
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/ans_pubs/938/2019_Ahn_PreparationCharacterizationManuscript.pdf|||Sat Jan 15 02:32:09 UTC 2022
dc.source.uri 10.1016/j.ijbiomac.2018.10.215
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.disciplines Poultry or Avian Science
dc.subject.keywords wound healing
dc.subject.keywords eggshell membrane
dc.subject.keywords antibacterial activity
dc.title Preparation and characterization of novel eggshell membrane-chitosan blend films for potential wound-care dressing: From waste to medicinal products
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication d3386101-2f0d-4375-ab44-ac1addb6a9ad
relation.isOrgUnitOfPublication 85ecce08-311a-441b-9c4d-ee2a3569506f
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