On-chip development of hydrogel microfibers from round to square/ribbon shape

dc.contributor.author Bai, Zhenhua
dc.contributor.author Mendoza Reyes, Janet
dc.contributor.author Hashemi, Nicole
dc.contributor.author Montazami, Reza
dc.contributor.author Hashemi, Nicole
dc.contributor.department Mechanical Engineering
dc.date 2018-11-18T05:50:40.000
dc.date.accessioned 2020-06-30T06:04:41Z
dc.date.available 2020-06-30T06:04:41Z
dc.date.copyright Wed Jan 01 00:00:00 UTC 2014
dc.date.issued 2014-01-01
dc.description.abstract <p>We use a microfluidic approach to fabricate gelatin fibers with controlled sizes and cross-sections. Uniform gelatin microfibers with various morphologies and cross-sections (round and square) are fabricated by increasing the gelatin concentration of the core solution from 8% to 12%. Moreover, the increase of gelatin concentration greatly improves the mechanical properties of gelatin fibers; the Young's modulus and tensile stress at break of gelatin (12%) fibers are raised about 2.2 and 1.9 times as those of gelatin (8%) fibers. The COMSOL simulations indicate that the sizes and cross-sections of the gelatin fibers can be tuned by using a microfluidic device with four-chevron grooves. The experimental results demonstrate that the decrease of the sheath-to-core flow-rate ratio from 150 : 1 to 30 : 1 can increase the aspect ratio and size of ribbon-shaped fibers from 35 μm × 60 μm to 47 μm × 282 μm, which is consistent with the simulation results. The increased size and shape evolution of the cross-section can not only strengthen the Young's modulus and tensile stress at break, but also significantly enhance the tensile strain at break.</p>
dc.description.comments <p>This is a manuscript of an article published as Bai, Zhenhua, Janet M. Mendoza Reyes, Reza Montazami, and Nastaran Hashemi. "On-chip development of hydrogel microfibers from round to square/ribbon shape." <em>Journal of Materials Chemistry A</em> 2, no. 14 (2014): 4878-4884. DOI: <a href="https://dx.doi.org/10.1039/C3TA14573E" target="_blank">10.1039/C3TA14573E</a>. Posted with permission.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/me_pubs/303/
dc.identifier.articleid 1307
dc.identifier.contextkey 13322953
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath me_pubs/303
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/55169
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/me_pubs/303/2014_Hashemi_OnChip.pdf|||Fri Jan 14 23:28:36 UTC 2022
dc.source.uri 10.1039/C3TA14573E
dc.subject.disciplines Applied Mechanics
dc.subject.disciplines Biology and Biomimetic Materials
dc.subject.disciplines Biomechanical Engineering
dc.subject.disciplines Polymer and Organic Materials
dc.title On-chip development of hydrogel microfibers from round to square/ribbon shape
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication f1ba9f2a-a64d-43aa-97ca-0d72675c4f2e
relation.isOrgUnitOfPublication 6d38ab0f-8cc2-4ad3-90b1-67a60c5a6f59
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