Murine Itk SH3 domain
| dc.contributor.author | Andreotti, Amy | |
| dc.contributor.author | Fulton, D. Bruce | |
| dc.contributor.author | Severin, Andrew | |
| dc.contributor.department | Roy J. Carver Department of Biochemistry, Biophysics and Molecular Biology (CALS) | |
| dc.contributor.department | Biochemistry, Biophysics and Molecular Biology, Roy J. Carver Department of | |
| dc.date | 2018-02-20T16:34:09.000 | |
| dc.date.accessioned | 2020-06-29T23:46:16Z | |
| dc.date.available | 2020-06-29T23:46:16Z | |
| dc.date.copyright | Tue Jan 01 00:00:00 UTC 2008 | |
| dc.date.issued | 2008-04-01 | |
| dc.description.abstract | <p>Interleukin-2 tyrosine kinase (Itk) is a non-receptor tyrosine kinase of the Tec family that is activated upon antigen binding to the T cell receptor (Schwartzberg et al. 2005; Berg 2007). Itk is comprised of four regulatory domains: PH (Pleckstrin homology), TH (Tec homology), SH3, SH2 and the catalytic kinase domain. SH3 domains share a common fold consisting of five anti-parallel β strands that form a β barrel and bind canonical proline rich ligands as well as a variety of noncanonical ligands (Agrawal and Kishan 2002).</p> | |
| dc.description.comments | <p>This is a post-peer-review, pre-copyedit version of an article published in Journal of Biomolecular NMR. The final authenticated version is available online at: <a href="http://dx.doi.org/10.1117/12.911289" target="_blank">http://dx.doi.org/10.1007/s10858-008-9231-9</a>.</p> | |
| dc.format.mimetype | application/pdf | |
| dc.identifier | archive/lib.dr.iastate.edu/bbmb_ag_pubs/185/ | |
| dc.identifier.articleid | 1201 | |
| dc.identifier.contextkey | 11597486 | |
| dc.identifier.s3bucket | isulib-bepress-aws-west | |
| dc.identifier.submissionpath | bbmb_ag_pubs/185 | |
| dc.identifier.uri | https://dr.lib.iastate.edu/handle/20.500.12876/10649 | |
| dc.language.iso | en | |
| dc.source.bitstream | archive/lib.dr.iastate.edu/bbmb_ag_pubs/185/2008_Andreotti_MurineDomainManuscript.pdf|||Fri Jan 14 21:43:02 UTC 2022 | |
| dc.source.uri | 10.1007/s10858-008-9231-9 | |
| dc.subject.disciplines | Biochemistry | |
| dc.subject.disciplines | Biophysics | |
| dc.subject.disciplines | Molecular Biology | |
| dc.subject.disciplines | Structural Biology | |
| dc.title | Murine Itk SH3 domain | |
| dc.type | article | |
| dc.type.genre | article | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 97143b55-8496-4365-8699-e254a8ac0903 | |
| relation.isAuthorOfPublication | 87268d62-4b33-4949-a936-2d6d1ff1cfe2 | |
| relation.isOrgUnitOfPublication | c70f85ae-e0cd-4dce-96b5-4388aac08b3f |
File
Original bundle
1 - 1 of 1
No Thumbnail Available
- Name:
- 2008_Andreotti_MurineDomainManuscript.pdf
- Size:
- 1 MB
- Format:
- Adobe Portable Document Format
- Description: