Murine Itk SH3 domain Andreotti, Amy Fulton, D. Bruce Severin, Andrew
dc.contributor.department Biochemistry, Biophysics and Molecular Biology 2018-02-20T16:34:09.000 2020-06-29T23:46:16Z 2020-06-29T23:46:16Z Tue Jan 01 00:00:00 UTC 2008 2008-04-01
dc.description.abstract <p>Interleukin-2 tyrosine kinase (Itk) is a non-receptor tyrosine kinase of the Tec family that is activated upon antigen binding to the T cell receptor (Schwartzberg et al. 2005; Berg 2007). Itk is comprised of four regulatory domains: PH (Pleckstrin homology), TH (Tec homology), SH3, SH2 and the catalytic kinase domain. SH3 domains share a common fold consisting of five anti-parallel β strands that form a β barrel and bind canonical proline rich ligands as well as a variety of noncanonical ligands (Agrawal and Kishan 2002).</p>
dc.description.comments <p>This is a post-peer-review, pre-copyedit version of an article published in Journal of Biomolecular NMR. The final authenticated version is available online at: <a href="" target="_blank"></a>.</p>
dc.format.mimetype application/pdf
dc.identifier archive/
dc.identifier.articleid 1201
dc.identifier.contextkey 11597486
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath bbmb_ag_pubs/185
dc.language.iso en
dc.source.bitstream archive/|||Fri Jan 14 21:43:02 UTC 2022
dc.source.uri 10.1007/s10858-008-9231-9
dc.subject.disciplines Biochemistry
dc.subject.disciplines Biophysics
dc.subject.disciplines Molecular Biology
dc.subject.disciplines Structural Biology
dc.title Murine Itk SH3 domain
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 97143b55-8496-4365-8699-e254a8ac0903
relation.isAuthorOfPublication 87268d62-4b33-4949-a936-2d6d1ff1cfe2
relation.isOrgUnitOfPublication c70f85ae-e0cd-4dce-96b5-4388aac08b3f
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
1 MB
Adobe Portable Document Format