Prospective study of alcohol consumption and the incidence of the metabolic syndrome in US men

dc.contributor.author Stoutenberg, Mark
dc.contributor.author Lee, Duck-Chul
dc.contributor.author Sui, Xuemei
dc.contributor.author Hooker, Steven
dc.contributor.author Horigian, Viviana
dc.contributor.author Perrino, Tatiana
dc.contributor.author Blair, Steven
dc.contributor.department Kinesiology
dc.date 2018-02-15T19:43:35.000
dc.date.accessioned 2020-06-30T05:45:49Z
dc.date.available 2020-06-30T05:45:49Z
dc.date.copyright Tue Jan 01 00:00:00 UTC 2013
dc.date.embargo 2015-02-04
dc.date.issued 2013-01-23
dc.description.abstract <p>Few studies have evaluated the effects of alcohol consumption on the incidence of the metabolic syndrome (MetS). Therefore, the objective of the present study was to examine the association between alcohol consumption and incident MetS in a population of US men. This is a prospective study of 7483 Caucasian men, who were free of the MetS and CVD at baseline. Information was collected on alcohol consumption, health status and fitness level at an initial clinical examination. Additional health information and determination of incident cases of the MetS were obtained at follow-up clinical examinations between 1979 and 2005. Compared with non-drinkers, the multivariate hazard ratios of the MetS for light (1–3 drinks/week), moderate (4–7 drinks/week), moderate–heavy (8–13 drinks/week) and heavy ( ≥ 14 drinks/week) drinkers were 0·81 (95 % CI 0·68, 0·95), 0·68 (95 % CI 0·57, 0·80), 0·70 (95 % CI 0·59, 0·83) and 0·78 (95 % CI 0·66, 0·91), respectively. This association was seen across age groups, in men with one or more pre-existing MetS risk factors, and those with BMI ≥ 25 kg/m<sup>2</sup>, and in all alcohol beverage types at most levels of alcohol consumption. An inverse dose–response association between alcohol consumption and low HDL concentrations was observed, while significant associations were observed between high fasting glucose concentrations and moderate, moderate–heavy and heavy levels of alcohol consumption. Alcohol consumption was not significantly associated with central obesity, hypertriacylglycerolaemia or hypertension. All levels of alcohol consumption provided significant inverse associations with incidence of the MetS. In particular, this effect was observed in overweight and/or obese individuals, in those who had pre-existing risk factors for the MetS, and extended across all types of alcoholic beverages consumed.</p>
dc.description.comments <p>This article is from <em>British Journal of Nutrition, 110(5)2013:901-910. Doi:</em><a href="http://dx.doi.org/10.1017/S0007114512005764%20" target="_blank">10.1017/S0007114512005764</a>. Posted with permission. </p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/kin_pubs/7/
dc.identifier.articleid 1005
dc.identifier.contextkey 6606301
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath kin_pubs/7
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/52550
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/kin_pubs/7/2013_LeeDC_ProspectiveStudy.pdf|||Sat Jan 15 01:33:36 UTC 2022
dc.source.uri 10.1017/S0007114512005764
dc.subject.disciplines Exercise Science
dc.subject.disciplines Expeditionary Education
dc.subject.disciplines Human and Clinical Nutrition
dc.subject.disciplines Kinesiology
dc.subject.keywords Alcohol
dc.subject.keywords Metabolic syndrome
dc.subject.keywords CVD risk factors
dc.subject.keywords Prospective studies
dc.title Prospective study of alcohol consumption and the incidence of the metabolic syndrome in US men
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 4b9a255a-7593-4589-b7fa-5bdb5817d9d7
relation.isOrgUnitOfPublication f7b0f2ca-8e43-4084-8a10-75f62e5199dd
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