Development and refinement of a technique for short-term intravascular auricular vein catheter placement in mature sows

dc.contributor.author Karriker, Locke
dc.contributor.author Butters-Johnson, Anna
dc.contributor.author Pairis-Garcia, Monique
dc.contributor.author Johnson, Anna
dc.contributor.author Bates, Jessica
dc.contributor.author Stock, Matthew
dc.contributor.author Stalder, Kenneth
dc.contributor.author Barth, L. A.
dc.contributor.author Brommel, Alyssa
dc.contributor.author Stalder, Kenneth
dc.contributor.author Karriker, Locke
dc.contributor.department Animal Science
dc.date 2018-02-16T21:23:34.000
dc.date.accessioned 2020-06-29T23:38:15Z
dc.date.available 2020-06-29T23:38:15Z
dc.date.copyright Wed Jan 01 00:00:00 UTC 2014
dc.date.issued 2014-01-01
dc.description.abstract <p>Intravenous drug administration in adult swine is difficult to perform due to inaccessible superficial veins and thick subcutaneous fat layers. However, successful intravenous drug administration is critical for many biomedical applications including pharmacokinetic studies as extravascular drug administration can influence the drug’s absorption and elimination rate. The purpose of this study was to develop and refine an effective technique for indwelling auricular vein catheter placement in the conscious mature sow. We developed a protocol using a topical anesthetic cream and minimal physical restraint to place indwelling catheters in the auricular vein of six multiparous sows. This method was quick (3 min 20 s ± 8 s [mean ± SE per catheter]), effective (11/12 catheters successfully placed) and reliable, allowing a large drug volume (20–22 mL) to be administrated successfully during the trial without relying on prolonged restraint or general anesthesia of the sow.</p>
dc.description.comments <p>This is a manuscript of an article in <em>Laboratory Animals</em> 48 (2014): 78, doi:<a href="http://dx.doi.org/10.1177/0023677213514044" target="_blank">10.1177/0023677213514044</a>. Posted with permission.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/ans_pubs/111/
dc.identifier.articleid 1113
dc.identifier.contextkey 7440893
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_pubs/111
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/9508
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/ans_pubs/111/2014_Butters_DevelopmentRefinement.pdf|||Fri Jan 14 18:42:14 UTC 2022
dc.source.uri 10.1177/0023677213514044
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.disciplines Large or Food Animal and Equine Medicine
dc.subject.disciplines Meat Science
dc.subject.keywords catheterization
dc.subject.keywords auricular vein
dc.subject.keywords sow
dc.subject.keywords refinement
dc.title Development and refinement of a technique for short-term intravascular auricular vein catheter placement in mature sows
dc.type article
dc.type.genre article
dspace.entity.type Publication
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relation.isOrgUnitOfPublication 85ecce08-311a-441b-9c4d-ee2a3569506f
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