Swine vesicular disease is a viral disease, characterized by the formation of vesicles and erosions, that affects only pigs. Although it can cause mild to severe illness, this infection is transient and not life-threatening. Its main significance is the strong resemblance to other vesicular diseases, particularly foot-and-mouth disease. Rapid differentiation of these diseases is critical, as the introduction of foot-andmouth disease could cause severe economic losses in non-endemic regions. In addition, the stability of swine vesicular disease virus in the environment complicates its eradication and makes prompt recognition essential for control.