Effects of Dietary Fatty Acids on Gene Expression and Biological Processes in Different Tissues of Pigs: A Review

dc.contributor.author Fanalli, Simara Larissa
dc.contributor.author da Silva, Bruna Pereira Martins
dc.contributor.author Petry, Bruna
dc.contributor.author Santana, Miguel Henrique de Almeida
dc.contributor.author Polizel, Guilherme Henrique Gebim
dc.contributor.author Antunes, Robson Carlos
dc.contributor.author de Almeida, Vivian Vezzoni
dc.contributor.author Moreira, Gabriel Costa Monteiro
dc.contributor.author Luchiari Filho, Albino
dc.contributor.author Coutinho, Luiz Lehmann
dc.contributor.author Balieiro, Júlio Cesar de Carvalho
dc.contributor.author Reecy, Mark
dc.contributor.author Koltes, James
dc.contributor.author Koltes, Dawn
dc.contributor.author Cesar, Aline Silva Mello
dc.contributor.department Animal Science
dc.date.accessioned 2022-01-31T16:30:21Z
dc.date.available 2022-01-31T16:30:21Z
dc.date.issued 2021-11-16
dc.description.abstract Studies on the influence of dietary components and their effects are fundamental for nutrigenomics, or the study of how nutrients can be cellular sensors, how they affect biological processes and gene expression in different tissues. Lipids are an important source of fatty acids (FA) and energy and are fundamental to biological processes and influence the regulation of transcription. Pigs are excellent model to study nutrigenomics, particularly lipid metabolism because the deposition and composition of FA in their tissues reflect the composition of FA in their diet. Recent studies show that FA supplementation is important in production systems, such as growing and finishing pigs, as it can improve the energy value of the feed, help reduce costs, improve animal welfare, and influence the nutritional value of the meat. Studies show that oleic (OA), linoleic (LA), docosahexaenoic (DHA), and eicosapentaenoic (EPA) acids are associated with the regulation of transcription in tissues such as muscle, liver, adipose tissue, and brain. Other studies indicate that EPA and DHA are associated with changes in specific signaling pathways, altering gene expression and biophysical properties of membranes. This review, therefore, focuses on the current knowledge of the effects of dietary FA on production traits and gene expression.
dc.description.comments This preprint is made available through Preprints, doi:10.20944/preprints202111.0279.v1. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/4vGXBW2r
dc.language.iso en
dc.publisher © Author(s) 2022
dc.source.uri https://doi.org/10.20944/preprints202111.0279.v1 *
dc.subject.disciplines DegreeDisciplines::Life Sciences::Animal Sciences
dc.subject.disciplines DegreeDisciplines::Life Sciences::Genetics and Genomics
dc.subject.disciplines DegreeDisciplines::Life Sciences::Physiology
dc.subject.keywords animal model
dc.subject.keywords dietary components
dc.subject.keywords feeding strategy
dc.subject.keywords gene expression
dc.subject.keywords lipid profile
dc.subject.keywords nutrients
dc.subject.keywords nutrigenomic
dc.subject.keywords physiological processes
dc.subject.keywords signaling pathways
dc.subject.keywords transcription
dc.title Effects of Dietary Fatty Acids on Gene Expression and Biological Processes in Different Tissues of Pigs: A Review
dc.type Preprint
dspace.entity.type Publication
relation.isAuthorOfPublication fb994cd9-94d5-4370-94ab-f33934c4cd6f
relation.isOrgUnitOfPublication 85ecce08-311a-441b-9c4d-ee2a3569506f
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