On Feb. 10, 1953, a ten-year-old male boxer was admitted to the Stange Memorial Clinic with many small urticarial- like swellings in the skin of the entire body. A large growth, one and one-half inches in diameter, was in the skin of the back. Some of the swellings were reported to have existed for only a short time, while others were quite firm in consistency and more persistent in growth. The condition had been noted for approximately two months by the owner and was diagnosed by a local veterinarian as urticaria. Antihistamine treatment had been administered without benefit.