Pig welfare from farm to slaughter can be defined by the stress the animals undergo when faced with new environments. Recent reports concerning animal welfare during transport and at the time of slaughter in Greece indicate that corrective actions should be taken by the Greek authorities in particular to supervision and monitoring the situation of transportation, resting and stunning of animals. Slaughter pigs are currently subjected to number of handing practices from the moment they leave their fattening pen until they stunned at slaughter. New management practices taking into account animal welfare during pre-slaughter and stunning (fasting, loading, transport, lairage, stunning system) must be adopted in order to limit animal stress from farm to slaughter. Some of these practices (equipment, logistics, training of the personnel) to be implemented are discussed. Apart of the issue of the animal welfare, the lack of adequate preparation of pigs on farm (fasting) and the use of poor handling systems throughout the pre-slaughter period also lead to carcass depreciation and meat quality defects (PSE, DFD) which reflect in great economic losses for the industry.