Review: Effects of Ractopamine Hydrochloride (Paylean) on welfare indicators for market weight pigs

dc.contributor.author Ritter, M. J.
dc.contributor.author Johnson, A. K.
dc.contributor.author Johnson, Anna
dc.contributor.author Benjamin, M. E.
dc.contributor.author Carr, S. N.
dc.contributor.author Ellis, M.
dc.contributor.author Faucitano, L.
dc.contributor.author Grandin, T.
dc.contributor.author Salak-Johnson, J. L.
dc.contributor.author Thomson, D. U.
dc.contributor.author Goldhawk, C.
dc.contributor.author Calvo-Lorenzo, M. S.
dc.contributor.department Animal Science
dc.date 2018-02-21T02:11:47.000
dc.date.accessioned 2020-06-29T23:40:06Z
dc.date.available 2020-06-29T23:40:06Z
dc.date.copyright Sun Jan 01 00:00:00 UTC 2017
dc.date.issued 2017-12-01
dc.description.abstract <p>This review summarizes the effects of ractopamine hydrochloride (RAC) dose (5, 7.5, 10, and 20 mg/kg) on market weight pig welfare indicators. Ractopamine hydrochloride (trade name Paylean) is a β-adrenergic agonist that was initially approved in the U.S. in 1999 at doses of 5 to 20 mg/kg to improve feed efficiency and carcass leanness. However, anecdotal reports suggested that RAC increased the rate of non-ambulatory (fatigued and injured) pigs at U.S. packing plants. This led to the addition of a caution statement to the Paylean label, and a series of research studies investigating the effects of RAC on pig welfare. Early research indicated that: (1) regardless of RAC administration, fatigued (non-ambulatory, non-injured) pigs are in a state of metabolic acidosis; (2) aggressive handling increases stress responsiveness at 20 mg/kg RAC, while 5 mg/kg reduces stress responsiveness to aggressive handling. Given this information, dosage range for Paylean was changed in 2006 to 5 to 10 mg/kg in market weight pigs. Subsequent research on RAC demonstrated that: (1) RAC has minimal effects on mortality, lameness, and home pen behavior; (2) RAC fed pigs demonstrated inconsistent prevalence and intensity of aggressive behaviors; (3) RAC fed pigs may be more difficult to handle at doses above 5 mg/kg; and (4) RAC fed pigs may have increased stress responsiveness and higher rates of non-ambulatory pigs when subjected to aggressive handling, especially when 20 mg/kg of RAC is fed.</p>
dc.description.comments <p>This article is published as Ritter, M. J., A. K. Johnson, M. E. Benjamin, S. N. Carr, M. Ellis, L. Faucitano, T. Grandin et al. "Effects of Ractopamine Hydrochloride (Paylean) on welfare indicators for market weight pigs." <em>Translational Animal Science</em> 1, no. 4 (2017): 533-558. doi: <a href="https://doi.org/10.2527/tas2017.0060">10.2527/tas2017.0060</a>. Posted with permission.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/ans_pubs/348/
dc.identifier.articleid 1349
dc.identifier.contextkey 11601005
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_pubs/348
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/9767
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/ans_pubs/348/2017_Johnson_ReviewEffects.pdf|||Fri Jan 14 23:42:52 UTC 2022
dc.source.uri 10.2527/tas2017.0060
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Sciences
dc.subject.disciplines Veterinary Physiology
dc.subject.keywords beta-agonist
dc.subject.keywords handling
dc.subject.keywords ractopamine
dc.subject.keywords swine
dc.subject.keywords welfare
dc.title Review: Effects of Ractopamine Hydrochloride (Paylean) on welfare indicators for market weight pigs
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 9459ddeb-303d-4035-933f-925ec181c7a6
relation.isOrgUnitOfPublication 85ecce08-311a-441b-9c4d-ee2a3569506f
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