A Coarse Techno-Economic Model of a Combined Fermentation-Catalysis Route to Sorbic Acid

dc.contributor.author Claypool, Joshua
dc.contributor.author Raman, D. Raj
dc.contributor.department Department of Agricultural and Biosystems Engineering (ENG)
dc.date 2018-02-13T03:43:18.000
dc.date.accessioned 2020-06-29T22:34:42Z
dc.date.available 2020-06-29T22:34:42Z
dc.date.copyright Sun Jan 01 00:00:00 UTC 2012
dc.date.embargo 2012-12-07
dc.date.issued 2012-07-01
dc.description.abstract <p>The conversion of biomass into bulk chemicals provides the potential for multiple environmental and economic benefits. While current research in industrial biotechnology focuses primarily on biocatalysts, a significant opportunity exists when combining biological and chemical catalysis into one process train. This hybrid process approach will potentially produce a wide array of economically viable molecules. One test-case of this hybrid approach is the production of sorbic acid via biocatalytic conversion of glucose to 4-Hydroxy-6-methyl-2-pyrone (HMP), followed by catalytic conversion of HMP to sorbic acid. Current collaborative research has developed this process to the stage where gram-quantities of biologically-produced HMP have been delivered to catalysis to produce butyl sorbate (a hydrolysis step can then take this to sorbic acid). Although the final process details needed for a detailed technoeconomic analyses are several years away, it is desirable to understand a coarse structure of the economics of such a process. Such an understanding can provide insight into opportunities for process improvement, as well as into fundamental technoeconomic limitations of the approach. To this end, we have developed a spreadsheet-based model of this hybrid process and have estimated the sorbic acid production cost from the process, which are then compared to current wholesale prices. We also report results of a comprehensive sensitivity analysis to demonstrate potential process improvements.</p>
dc.description.comments <p>This is an ASABE Meeting Presentation, Paper No. <a href="http://elibrary.asabe.org/abstract.asp?aid=41800&t=3&dabs=Y&redir=&redirType=" target="_blank">12-1337523</a>.</p>
dc.identifier archive/lib.dr.iastate.edu/abe_eng_conf/48/
dc.identifier.articleid 1047
dc.identifier.contextkey 3522262
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath abe_eng_conf/48
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/515
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/abe_eng_conf/48/Raman_2012_CoarseTechnoEconomicModel.pdf|||Sat Jan 15 00:26:41 UTC 2022
dc.source.uri 10.13031/2013.41800
dc.subject.disciplines Agriculture
dc.subject.disciplines Bioresource and Agricultural Engineering
dc.subject.keywords Model
dc.subject.keywords Industrial Biotechnology
dc.subject.keywords Sorbic Acid
dc.subject.keywords 4-Hydroxy-6-Methyl-2-Pyrone
dc.subject.keywords Techno-economic
dc.title A Coarse Techno-Economic Model of a Combined Fermentation-Catalysis Route to Sorbic Acid
dc.type article
dc.type.genre conference
dspace.entity.type Publication
relation.isAuthorOfPublication 0d20027b-c384-4033-aafe-d7cf62e10240
relation.isOrgUnitOfPublication 8eb24241-0d92-4baf-ae75-08f716d30801
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