A brief review of vertebrate sex evolution with a pledge for integrative research: towards ‘sexomics’

dc.contributor.author Stöck, Matthias
dc.contributor.author Kratochví, Lukáš
dc.contributor.author Kuhl, Heiner
dc.contributor.author Rovatsos, Michail
dc.contributor.author Evans, Ben J.
dc.contributor.author Suh, Alenxander
dc.contributor.author Valenzuela, Nicole
dc.contributor.author Veyrunes, Frédéric
dc.contributor.author Zhou, Qi
dc.contributor.author Gamble, Tony
dc.contributor.author Capel, Blanche
dc.contributor.author Schartl, Manfred
dc.contributor.author Guiguen, Yann
dc.contributor.department Ecology, Evolution and Organismal Biology
dc.date.accessioned 2022-04-04T17:21:09Z
dc.date.available 2022-04-04T17:21:09Z
dc.date.issued 2021-07-12
dc.description.abstract Triggers and biological processes controlling male or female gonadal differentiation vary in vertebrates, with sex determination (SD) governed by environmental factors or simple to complex genetic mechanisms that evolved repeatedly and independently in various groups. Here, we review sex evolution across major clades of vertebrates with information on SD, sexual development and reproductive modes. We offer an up-to-date review of divergence times, species diversity, genomic resources, genome size, occurrence and nature of polyploids, SD systems, sex chromosomes, SD genes, dosage compensation and sex-biased gene expression. Advances in sequencing technologies now enable us to study the evolution of SD at broader evolutionary scales, and we now hope to pursue a sexomics integrative research initiative across vertebrates. The vertebrate sexome comprises interdisciplinary and integrated information on sexual differentiation, development and reproduction at all biological levels, from genomes, transcriptomes and proteomes, to the organs involved in sexual and sex-specific processes, including gonads, secondary sex organs and those with transcriptional sex-bias. The sexome also includes ontogenetic and behavioural aspects of sexual differentiation, including malfunction and impairment of SD, sexual differentiation and fertility. Starting from data generated by high-throughput approaches, we encourage others to contribute expertise to building understanding of the sexomes of many key vertebrate species. This article is part of the theme issue ‘Challenging the paradigm in sex chromosome evolution: empirical and theoretical insights with a focus on vertebrates (Part I)’.
dc.description.comments This article is published as Stöck M et al. 2021 A brief review of vertebrate sex evolution with a pledge for integrative research: towards ‘sexomics’. Phil. Trans. R. Soc. B 376: 20200426. https://doi.org/10.1098/rstb.2020.0426. Posted with permission. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/gwW7ADMw
dc.language.iso en
dc.publisher © 2021 The Authors
dc.source.uri https://doi.org/10.1098/rstb.2020.0426 *
dc.subject.keywords developmental biology
dc.subject.keywords genetics
dc.subject.keywords evolution
dc.subject.keywords genomics
dc.title A brief review of vertebrate sex evolution with a pledge for integrative research: towards ‘sexomics’
dc.type Article
dspace.entity.type Publication
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relation.isOrgUnitOfPublication fb57c4c9-fba7-493f-a416-7091a6ecedf1
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