Potential of bacteriophage application as an intervention strategy against Salmonella in pigs

Abstract

<p>Bacteriophage (phage) lysate was used for reducing the dissemination of <em>Salmonella</em> in pigs. The phage lysate was administrated into pigs beginning 1 hour after challenge for 2-hour duration. Three hours postchallenge, pigs were killed and necropsied. The numbers of <em>Salmonella</em> were enumerated in various tissue samples. Administration of the phage lysate lowered the numbers of <em>Salmonella</em> by 2 logs compared with controls in the colon and cecum contents. It suggests that use of phage could be considered as an alternative intervention strategy against<em> Salmonella</em> in pigs at the preharvest stage with further studies.</p>