Recognition and protection of glycosphingolipids by synthetic nanoparticle receptors
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2019-01-01
Authors
Gunasekara, Roshan
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Abstract
Nanoparticle receptors were synthesized through micellar imprinting to bind glycosphingolipids with 20–140 μM binding affinities, meanwhile distinguishing glycan composition, the number of acyl chains, and hydroxylation of acyl chains in the lipids. The strong binding enabled the receptors to protect their target glycolipids dispersed in lipid membranes from enzymatic degradation.
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This article is published as Gunasekara, Roshan W., and Yan Zhao. "Recognition and protection of glycosphingolipids by synthetic nanoparticle receptors." Chemical Communications 55, no. 33 (2019): 4773-4776. DOI: 10.1039/C9CC01694E. Posted with permission.
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Tue Jan 01 00:00:00 UTC 2019