Molecularly Responsive Binding through Co-occupation of Binding Space: A Lock–Key Story

Thumbnail Image
Date
2016-01-01
Authors
Awino, Joseph
Hu, Lan
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract

When two guest molecules co-occupy a binding pocket of a water-soluble host, the first guest could be used as a signal molecule to turn on the binding of the second. This type of molecularly responsive binding strongly depends on the size of the two guests and the location of the signal molecule.

Series Number
Journal Issue
Is Version Of
Versions
Series
Academic or Administrative Unit
Type
article
Comments

This is a manuscript of an article published as Awino, Joseph K., Lan Hu, and Yan Zhao. "Molecularly Responsive Binding through Co-occupation of Binding Space: A Lock–Key Story." Organic letters 18, no. 7 (2016): 1650-1653. doi:10.1021/acs.orglett.6b00527. Posted with permission.

Rights Statement
Copyright
Fri Jan 01 00:00:00 UTC 2016
Funding
Subject Categories
DOI
Supplemental Resources
Collections