Mitigation of Airborne PRRSV Transmission with UV Light Treatment: Proof-of-Concept

dc.contributor.author Hoff, Steven
dc.contributor.author Koziel, Jacek
dc.contributor.author Li, Peiyang
dc.contributor.author Koziel, Jacek
dc.contributor.author Zimmerman, Jeffrey
dc.contributor.author Zhang, Jianqiang
dc.contributor.author Cheng, Ting-Yu
dc.contributor.author Yim-Im, Wannarat
dc.contributor.author Jenks, William
dc.contributor.author Lee, Myeongseong
dc.contributor.author Jenks, William
dc.contributor.author Chen, Baitong
dc.contributor.author Hoff, Steven
dc.contributor.department Food Science and Human Nutrition
dc.contributor.department Civil, Construction and Environmental Engineering
dc.contributor.department Chemistry
dc.contributor.department Veterinary Diagnostic and Production Animal Medicine
dc.contributor.department Agricultural and Biosystems Engineering
dc.contributor.department Environmental Science
dc.contributor.department Toxicology
dc.date 2021-04-07T23:21:23.000
dc.date.accessioned 2021-04-29T23:07:24Z
dc.date.available 2021-04-29T23:07:24Z
dc.date.copyright Fri Jan 01 00:00:00 UTC 2021
dc.date.issued 2021-03-18
dc.description.abstract <p>Proper treatment of infectious air could potentially mitigate the spread of airborne viruses such as porcine reproductive and respiratory syndrome virus (PRRSV). The objective of this research is to test the effectiveness of ultraviolet (UV) in inactivating aerosolized PRRSV, specifically, four UV lamps, UV-A (365 nm, both fluorescent and LED-based), “excimer” UV-C (222 nm), and germicidal UV-C (254 nm), were tested. The two UV-C lamps effectively irradiated fast-moving PRRSV aerosols with short treatment times (<2 s). One-stage and two-stage UV inactivation models estimated the UV doses needed for target percentage (%) reductions on PRRSV titer. UV-C (254 nm) dose needed for 3-log (99.9%) reduction was 0.521 and 0.0943 mJ/cm<sup>2</sup>, respectively, based on one-stage and two-stage models. An order of magnitude lower UV-C (222 nm) doses were needed for a 3-log reduction, i.e., 0.0882 and 0.048 mJ/cm<sup>2</sup>, based on one-stage and two-stage models, respectively. However, the cost of 222 nm excimer lamps is still economically prohibitive for scaling-up trials. The UV-A (365 nm) lamps could not reduce PRRSV titers for tested doses up to 4.11 mJ/cm<sup>2</sup>. Pilot-scale or farm-scale testing of UV-C on PRRSV aerosols simulating barn ventilation rates are recommended based on its effectiveness and reasonable costs comparable to HEPA filtration</p>
dc.description.comments <p>This article is published as Li, Peiyang, Jacek A. Koziel, Jeffrey J. Zimmerman, Jianqiang Zhang, Ting-Yu Cheng, Wannarat Yim-Im, William S. Jenks, Myeongseong Lee, Baitong Chen, and Steven J. Hoff. "Mitigation of Airborne PRRSV Transmission with UV Light Treatment: Proof-of-Concept." <em>Agriculture</em> 11, no. 3 (2021): 259. DOI: <a href="https://doi.org/10.3390/agriculture11030259" target="_blank">10.3390/agriculture11030259</a>. Posted with permission.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/abe_eng_pubs/1190/
dc.identifier.articleid 2475
dc.identifier.contextkey 21994583
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath abe_eng_pubs/1190
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/104449
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/abe_eng_pubs/1190/2021_KozielJacek_MitigationAirborne.pdf|||Mon Mar 08 20:14:27 UTC 2021
dc.source.bitstream archive/lib.dr.iastate.edu/abe_eng_pubs/1190/2021_KozielJacek_MitigationAirbornePRRSV.pdf|||Fri Jan 14 19:01:15 UTC 2022
dc.source.uri 10.3390/agriculture11030259
dc.subject.disciplines Agriculture
dc.subject.disciplines Bioresource and Agricultural Engineering
dc.subject.disciplines Environmental Chemistry
dc.subject.disciplines Veterinary Infectious Diseases
dc.subject.keywords air purification
dc.subject.keywords animal production
dc.subject.keywords porcine reproductive and respiratory syndrome
dc.subject.keywords livestock health
dc.subject.keywords livestock biosecurity
dc.subject.keywords swine diseases
dc.subject.keywords ultraviolet light
dc.title Mitigation of Airborne PRRSV Transmission with UV Light Treatment: Proof-of-Concept
dc.type article
dc.type.genre article
dspace.entity.type Publication
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