The purpose of this work was to evaluate the outcomes of Fashion FUNdamentals, a youth enrichment program that invokes fashion as a catalyst to ignite middle school girls' interest in STEM learning. FF is a two-week, no-cost, summer program (M-F, 9 am-5 pm) that targets underserved middle school girls (aged 11-14). The program addresses the multifaceted educational and developmental needs of middle school girls through both technical programming (i.e., STEM-based education in fiber/textile science; digital textile printing; apparel engineering; and apparel costing and pricing) and social programming (i.e., esteem-based education in body image/media literacy, nutrition, physical activity, anti-bullying, and Internet safety). Findings provide evidence that Fashion FUNdamentals has the potential to build girls' interest in math and science as well as their self-esteem. Girls who enter the program with either low or high self-esteem may benefit from participation relative to increased interest as an outcome.