A meta-analysis explains the variation in estimated trade effects of technical barriers to trade broadly defined, using available estimates from the empirical international trade literature, and accounting for data sampling and methodology differences. Agriculture and food industries tend to be more impeded by these barriers than other sectors. SPS regulations on agricultural trade flows from developing exporters to high-income importers tend to impede trade. Controlling for “multilateral resistance” lowers the propensity to find that these policies impede trade. Estimations correcting endogeneity by using panel data and time fixed effect yield more negative (or less positive) trade effects of technical measures.