Timed Up and Go, Cognitive, and Quality-of-Life Correlates in Parkinson’s Disease

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2014-04-01
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Stegemöller, Elizabeth
Nocera, Joe
Malaty, Irene
Okun, Michael
Hass, Chris
NPF Quality Improvement Initiative Investigators
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Shelley, Mack
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Stegemoller, Elizabeth
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Abstract

Objective: To examine the relationship between Timed Up and Go (TUG) performance, verbal executive function (EF) performance, and quality-of-life (QOL) measures in Parkinson's disease (PD).

Design: Cross-sectional.

Setting: Sixteen movement disorder centers from across the United States.

Participants: Patients with PD (N=1964).

Interventions: Not applicable.

Main Outcome Measures: TUG test, immediate and delayed 5-word recall, verbal fluency, PD QOL Questionnaire.

Results: TUG performance and verbal EF performance were significantly associated with, and predictors of, QOL measures, having the greatest association and predictability with the mobility domain of the QOL measures.

Conclusions: The TUG test and verbal EF tests have QOL correlates, making the combined evaluation of mobility, cognitive, and QOL decline a potential examination tool to evaluate the sequelae of PD.

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This article is published as Stegemöller, Elizabeth L., Joe Nocera, Irene Malaty, Mack Shelley, Michael S. Okun, Chris J. Hass, and NPF Quality Improvement Initiative Investigators. "Timed up and go, cognitive, and quality-of-life correlates in Parkinson's disease." Archives of Physical Medicine and Rehabilitation 95, no. 4 (2014): 649-655. DOI: 10.1016/j.apmr.2013.10.031.

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