Method of enhancing immune response of mammals

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1991-02-12
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Nissen, Steven
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Iowa State University Research Foundation, Inc.
The Iowa State University Research Foundation (ISURF) seeks to protect the intellectual property (including new discoveries, technologies, or creative works) of the university's students & faculty which is continuously created through research and other undertakings. It seeks to manage, protect, and own all intellectual property on behalf of the university. The Iowa State University Research Foundation was created in 1938.
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β-methyl-βbutyrate (HMB) has been found to be markedly more effective for activating the immune function of T lymphocytes of mammals than α-ketoisocaproate (KIC). For activation of the T lymphocytes, β-methyl-butyric acid or an edible water-soluble salt thereof is administered to the mammal by a route through which the HMB enters the blood of the mammal. The amount administered is sufficient for effective enhancement of the blastogenesis of their T lymphocytes. The method is adapted for use with domestic mammals, including particularly cattle, sheep, and swine. HMB can also be used with humans as an immune system stimulant.

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