Total Synthesis of Coriandrin
Total Synthesis of Coriandrin
Date
1994-08-01
Authors
Kraus, George
Ridgeway, James
Kraus, George
Ridgeway, James
Kraus, George
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Altmetrics
Authors
Kraus, George
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Research Projects
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Chemistry
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Chemistry
Abstract
Coriandrin, an antiviral agent, has been synthesized in nine steps from diketone 3. The key steps in the synthesis include an eficient aromatization reaction using N-bromosuccinimide and a palladium-mediated coupling of a benzylic bromide with a vinyl stannane.
Comments
Reprinted (adapted) with permission from The Journal of Organic Chemistry, 59(17); 4735-4737. Doi: 10.1021/jo00096a013. Copyright 1994 American Chemical Society.