Effects of dairy products on intestinal integrity in heat-stressed pigs

dc.contributor.author Sanz Fernandez, M. Victoria
dc.contributor.author Pearce, Sarah
dc.contributor.author Patience, John
dc.contributor.author Mani, Venkatesh
dc.contributor.author Gabler, Nicholas
dc.contributor.author Metzger, Lloyd
dc.contributor.author Patience, John
dc.contributor.author Rhoads, Robert
dc.contributor.author Baumgard, Lance
dc.contributor.department Animal Science
dc.date 2021-02-10T20:08:45.000
dc.date.accessioned 2021-02-24T21:14:39Z
dc.date.available 2021-02-24T21:14:39Z
dc.date.copyright Wed Jan 01 00:00:00 UTC 2014
dc.date.issued 2014-01-01
dc.description.abstract <p>Heat stress compromises intestinal integrity which may partially explain its negative effects on animal health and productivity. Research suggests that challenged intestinal barrier function improves with dietary dairy products in various models. Thus, the study objective was to evaluate the effects of bovine milk whey protein (WP) and colostral whey protein (CWP) on intestinal integrity in heat-stressed pigs. Crossbred gilts (39 ± 3 kg body weight) were fed 1 of 4 diets (n = 8 pigs/diet): control (Ct), control diet containing an 80% WP and 20% CWP product (WP80), control diet containing a 98% WP and 2% CWP product (WP98), and control diet containing a 100% WP product (WP100). After 7d on experimental diets, pigs were exposed to constant heat stress conditions (32 °C) for 24h. There were no treatment differences in growth or body temperature indices prior to heat stress. During heat exposure, both rectal temperature and respiration rate increased (+0.85 °C and 3-fold, respectively; <em>P</em> < 0.01), and feed intake and body weight decreased (44% and -0.5kg, respectively; <em>P</em> < 0.01), but neither variable was affected by dietary treatments. Plasma L-lactate and D-lactate concentrations increased (36%; <em>P</em> < 0.01) and tended to increase (19%; <em>P</em> = 0.09) with heat stress. After 24h of heat exposure, WP100-fed pigs had lower plasma D-lactate relative to Ct-fed pigs. Ileal transepithelial electrical resistance was decreased (37%; <em>P</em> = 0.02) in WP80 pigs, compared with controls. No differences were detected in other intestinal integrity ex vivo measurements. These data demonstrate that dietary WP and CWP did not mitigate intestinal integrity dysfunction during severe heat stress.</p>
dc.description.comments <p>This article is published as Sanz Fernandez, M. Victoria, Sarah C. Pearce, Venkatesh Mani, Nicholas K. Gabler, Lloyd Metzger, John F. Patience, Robert P. Rhoads, and Lance H. Baumgard. "Effects of dairy products on intestinal integrity in heat-stressed pigs." <em>Temperature</em> 1, no. 2 (2014): 128-134. doi:<a href="https://doi.org/10.4161/temp.29561">10.4161/temp.29561</a>.</p>
dc.format.mimetype application/pdf
dc.identifier archive/lib.dr.iastate.edu/ans_pubs/756/
dc.identifier.articleid 1755
dc.identifier.contextkey 21577174
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath ans_pubs/756
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/93511
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/ans_pubs/756/0-OA_license_for_2014_Patience_EffectsDairy.pdf|||Sat Jan 15 01:50:08 UTC 2022
dc.source.bitstream archive/lib.dr.iastate.edu/ans_pubs/756/2014_Patience_EffectsDairy.pdf|||Sat Jan 15 01:50:10 UTC 2022
dc.source.uri 10.4161/temp.29561
dc.subject.disciplines Agriculture
dc.subject.disciplines Animal Experimentation and Research
dc.subject.disciplines Animal Sciences
dc.subject.keywords pigs
dc.subject.keywords heat stress
dc.subject.keywords dairy products
dc.subject.keywords intestinal integrity
dc.title Effects of dairy products on intestinal integrity in heat-stressed pigs
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 5888d61a-1b3d-48c9-ab84-deb63aa3a43c
relation.isOrgUnitOfPublication 85ecce08-311a-441b-9c4d-ee2a3569506f
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