This study examined whether the relationship between depressive symptoms and relational outcomes such as marital satisfaction and perceived spousal social support reflect the influence of a third variable, negative affectivity. Specifically, the study addressed whether the effects of negative affectivity on these other self report measures extend over time. Negative affectivity, marital satisfaction, and perceived spousal social support were tested as predictors of depression. The sample included 178 married African American women participating in the FACHS study. Both perceived spousal support and marital satisfaction continued to significantly predict depression after controlling for negative affectivity at a previous time point. These findings suggest that the effects of negative affectivity appear to weaken over time.