PLATYHELMINTH PARASITES ARE COMMON PARASITES OF FISH, BOTH IN THE WILD AND IN AQUACULTURE SYSTEMS. THESE PARASITES INCLUDE CESTODES ALONG WITH MONOGENEAN AND DIGENEAN TREMATODES. PRAZIQUANTEL IS A DRUG WITH ANTI-FLATWORM ACTIVITY AND IS WIDELY USED IN HUMAN AND VETERINARY MEDICINE. AT THIS TIME PRAZIQUANTEL IS NOT APPROVED FOR THE USE IN FISH, BUT USE MAY BE JUSTIFIED UNDER THE GUIDANCE OF THE ANIMAL MEDICINAL DRUG USE CLARIFICATION ACT (AMDUCA). WHILE SOME STUDIES HAVE INVESTIGATED THE USE OF PRAZIQUANTEL IN AQUACULTURE, THERE ARE STILL SEVERAL GAPS IN THE KNOWLEDGE NEEDED FOR THE USE OF PRAZIQUANTEL IN FISH SPECIES.