Biaxial testing device for large animal tissue experiments
Date
2025-05
Authors
Liu, Changhao
Major Professor
Advisor
Ramachandra, Abhay
Kingston, Todd
Kirillova, Alina
Committee Member
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Abstract
A variety of approaches have been taken to carry out experiments involving animal tissue, both for small and large animals. One area of focus for animal tissue experiments is to determine the response of the tissue under various stresses, such as linear forces. Thanks to the use of sophisticated laboratory equipment, including mechanical devices, force transducers, and data acquisition systems, several experiment devices have been developed by various researchers over the years. One example studied as part of this research project is a planar biaxial testing device, which exerts opposing linear forces in two axes on a large animal tissue sample in the shape of a square. Improving upon the work of previous research, a new version is built at the Roy J. Carver Co-Laboratory at Iowa State University to conduct similar experiments. The construction and implementation of the planar biaxial testing device set the stage for a tubular biaxial testing device to also be developed, which is the basis for this research project. Like the planar biaxial device, the tubular biaxial device also improves upon the work of a previous researcher. Unlike the planar biaxial device, this device exerts opposing linear forces on a tube-shaped animal tissue sample represented using cylindrical coordinates. Opposing linear forces are only applied in one axis which determines the length, while the second axis involves filling the sample with fluid which determines the radius. The tubular biaxial testing device, along with the planar biaxial version, offers a pathway for mechanical engineering principles to be integrated with the field of animal science, allowing innovative solutions for experimenting with animal tissue.
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Mechanical Engineering
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article