Initializing Partition-Optimization Algorithms
Is Version Of
Clustering data sets is a challenging problem needed in a wide array of applications. Partition-optimization approaches, such as k-means or expectation-maximization (EM) algorithms, are suboptimal and find solutions in the vicinity of their initialization. This paper proposes a staged approach to specifying initial values by finding a large number of local modes and then obtaining representatives from the most separated ones. Results on test experiments are excellent. We also provide a detailed comparative assessment of the suggested algorithm with many commonly used initialization approaches in the literature. Finally, the methodology is applied to two data sets on diurnal microarray gene expressions and industrial releases of mercury.
This is a manuscript of an article from IEEE/ACM Transactions on Computational Biology and Bioinformatics 6 (2009): 144, doi: 10.1109/TCBB.2007.70244. Posted with permission. Copyright 2009 IEEE.