Fluorinated Analogs of Malachite Green: Synthesis and Toxicity
dc.contributor.author | Kraus, George | |
dc.contributor.author | Jeon, Insik | |
dc.contributor.author | Nilsen-Hamilton, Marit | |
dc.contributor.author | Awad, Ahmed | |
dc.contributor.author | Nilsen-Hamilton, Marit | |
dc.contributor.author | Parvin, Bahram | |
dc.contributor.department | Biochemistry, Biophysics and Molecular Biology | |
dc.contributor.department | Chemistry | |
dc.date | 2018-02-17T07:59:16.000 | |
dc.date.accessioned | 2020-06-30T01:19:36Z | |
dc.date.available | 2020-06-30T01:19:36Z | |
dc.date.copyright | Tue Jan 01 00:00:00 UTC 2008 | |
dc.date.issued | 2008-04-27 | |
dc.description.abstract | <p>A series of fluorinated analogs of malachite green (MG) have been synthesizedand their toxicity to Saccharomyces cerevisiae and a human ovarian epithelial cell lineexamined. The toxicity profiles were found to be different for these two species. Twoanalogs, one with 2,4-difluoro substitution and the other with 2-fluoro substitution seem tobe the most promising analogs because they showed the lowest toxicity to the human cells.</p> | |
dc.description.comments | <p>Reprinted (adapted) with permission from <em>Molecules,</em> 2008; 13(4); 986-994. Doi: <a href="http://dx.doi.org/10.3390/molecules13040986" target="_blank">10.3390/molecules13040986</a>. Posted with permission.</p> | |
dc.format.mimetype | application/pdf | |
dc.identifier | archive/lib.dr.iastate.edu/chem_pubs/363/ | |
dc.identifier.articleid | 1379 | |
dc.identifier.contextkey | 7925872 | |
dc.identifier.s3bucket | isulib-bepress-aws-west | |
dc.identifier.submissionpath | chem_pubs/363 | |
dc.identifier.uri | https://dr.lib.iastate.edu/handle/20.500.12876/14814 | |
dc.language.iso | en | |
dc.source.bitstream | archive/lib.dr.iastate.edu/chem_pubs/363/2008_KrausGA_FluorinatedAnalogsMalachite.pdf|||Fri Jan 14 23:47:46 UTC 2022 | |
dc.source.uri | 10.3390/molecules13040986 | |
dc.subject.disciplines | Chemistry | |
dc.subject.disciplines | Organic Chemistry | |
dc.subject.disciplines | Other Chemistry | |
dc.subject.disciplines | Polymer Chemistry | |
dc.subject.keywords | Malachite Green | |
dc.subject.keywords | Malachite Green analogs | |
dc.subject.keywords | Bathochromic shift | |
dc.subject.keywords | Toxicity | |
dc.subject.keywords | Saccharomyces cerevisiae | |
dc.subject.keywords | human ovarian epithelial cells. | |
dc.title | Fluorinated Analogs of Malachite Green: Synthesis and Toxicity | |
dc.type | article | |
dc.type.genre | article | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 773dd84a-1494-40ee-aebf-549f26a04a22 | |
relation.isAuthorOfPublication | c84e6eba-3eab-4cce-8d1e-80e67584729b | |
relation.isOrgUnitOfPublication | faf0a6cb-16ca-421c-8f48-9fbbd7bc3747 | |
relation.isOrgUnitOfPublication | 42864f6e-7a3d-4be3-8b5a-0ae3c3830a11 |
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