Salmonellosis is a threat to the whole pork production chain. Different risks factors have been associated with Salmonella contamination. The aim of this project was to assess the efficacy of a comprehensive control program in a 30 000 sows integrated company located in Canada, with an emphasis on pre-harvest control measures, to limit Salmonella pork carcasses contamination. Based on previous molecular epidemiology investigations, the main sources of contamination were identified as the environment and the replacement gilts. The features of this 10 years program consisted of : Sourcing with negative replacement gilts, use of mash coarse feed on gilt finishers and sow herds, application of detailed cleaning and disinfection procedures on all farms, transport vehicles, slaughtering facilities and accessories, respect of all-in all-out and single source.