Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease.

Date
2016-01-01
Authors
Dougherty, Ryan
Ellingson, Laura
Meyer, Jacob
Schultz, Stephanie
Boots, Elizabeth
Meyer, Jacob
Lindheimer, Jacob
Van Riper, Stephanie
Stegner, Aaron
Edwards, Dorothy
Oh, Jennifer
Koscik, Rebecca
Dowling, Maritza
Gallagher, Catherine
Carlsson, Cynthia
Rowley, Howard
Bendlin, Barbara
Asthana, Sanjay
Hermann, Bruce
Sager, Mark
Johnson, Sterling
Okonkwo, Ozioma
Cook, Dane
Major Professor
Advisor
Committee Member
Journal Title
Journal ISSN
Volume Title
Publisher
Altmetrics
Authors
Research Projects
Organizational Units
Kinesiology
Organizational Unit
Journal Issue
Series
Department
Kinesiology
Abstract

INTRODUCTION: Physical activity (PA) is associated with brain health in older adults. However, it is unknown whether the current physical activity recommendations (PAR) impart substantive benefit. The objective of this study was to compare temporal lobe volumes between older adults who met PAR and those who did not.

METHODS: Ninety-one enrollees from the Wisconsin Registry for Alzheimer's Prevention wore an accelerometer for seven consecutive days to quantify their PA behaviors and underwent a T-1 anatomic magnetic resonance imaging scan. Participants were categorized as either having met PAR or not based on the US Department of Health and Human Services recommendations of 150 minutes of moderate-to-vigorous physical activity per week.

RESULTS: Participants who met PAR possessed significantly greater inferior (η(2) P = .050) and anterior (η(2) P = .055) temporal lobe volumes compared with those who did not (P < .05).

DISCUSSION: Individuals at-risk for AD experience accelerated rates of brain atrophy. These results suggest that regular engagement in PA at or above PAR could attenuate this decline.

Comments

This article is published as Dougherty R, Ellingson L, Schultz S, Boots E, Meyer J, Lindheimer J, Van Riper S, Stegner A, Edwards D, Oh J, Koscik R, Dowling M, Gallagher C, Carlsson C, Rowley H, Bendlin B, Asthana S, Hermann B, Sager M, Johnson S, Okonkwo O, Cook D (2016). Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease. Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 4; 14-17. doi:10.1016/j.dadm.2016.03.005.

Description
Keywords
Citation
DOI
Collections