Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease.

dc.contributor.author Dougherty, Ryan
dc.contributor.author Ellingson, Laura
dc.contributor.author Meyer, Jacob
dc.contributor.author Schultz, Stephanie
dc.contributor.author Boots, Elizabeth
dc.contributor.author Meyer, Jacob
dc.contributor.author Lindheimer, Jacob
dc.contributor.author Van Riper, Stephanie
dc.contributor.author Stegner, Aaron
dc.contributor.author Edwards, Dorothy
dc.contributor.author Oh, Jennifer
dc.contributor.author Koscik, Rebecca
dc.contributor.author Dowling, Maritza
dc.contributor.author Gallagher, Catherine
dc.contributor.author Carlsson, Cynthia
dc.contributor.author Rowley, Howard
dc.contributor.author Bendlin, Barbara
dc.contributor.author Asthana, Sanjay
dc.contributor.author Hermann, Bruce
dc.contributor.author Sager, Mark
dc.contributor.author Johnson, Sterling
dc.contributor.author Okonkwo, Ozioma
dc.contributor.author Cook, Dane
dc.contributor.department Kinesiology
dc.date 2018-10-10T09:14:43.000
dc.date.accessioned 2020-06-30T05:45:35Z
dc.date.available 2020-06-30T05:45:35Z
dc.date.copyright Fri Jan 01 00:00:00 UTC 2016
dc.date.issued 2016-01-01
dc.description.abstract <p><h4>INTRODUCTION: <strong>Physical activity (PA) is associated with brain health in older adults. However, it is unknown whether the current physical activity recommendations (PAR) impart substantive benefit. The objective of this study was to compare temporal lobe volumes between older adults who met PAR and those who did not.</strong></h4> <h4>METHODS: Ninety-one enrollees from the Wisconsin Registry for Alzheimer's Prevention wore an accelerometer for seven consecutive days to quantify their PA behaviors and underwent a T-1 anatomic magnetic resonance imaging scan. Participants were categorized as either having met PAR or not based on the US Department of Health and Human Services recommendations of 150 minutes of moderate-to-vigorous physical activity per week.</h4> <h4>RESULTS: Participants who met PAR possessed significantly greater inferior (η(2) P = .050) and anterior (η(2) P = .055) temporal lobe volumes compared with those who did not (P < .05).</h4> <h4>DISCUSSION: Individuals at-risk for AD experience accelerated rates of brain atrophy. These results suggest that regular engagement in PA at or above PAR could attenuate this decline.</h4></p>
dc.description.comments <p>This article is published as Dougherty R, Ellingson L, Schultz S, Boots E, <strong>Meyer J</strong>, Lindheimer J, Van Riper S, Stegner A, Edwards D, Oh J, Koscik R, Dowling M, Gallagher C, Carlsson C, Rowley H, Bendlin B, Asthana S, Hermann B, Sager M, Johnson S, Okonkwo O, Cook D (2016). Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease. <em>Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring</em>, 4; 14-17. <a href="http://dx.doi.org/10.1016/j.dadm.2016.03.005">doi:10.1016/j.dadm.2016.03.005</a>. </p>
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dc.identifier archive/lib.dr.iastate.edu/kin_pubs/35/
dc.identifier.articleid 1035
dc.identifier.contextkey 13052087
dc.identifier.s3bucket isulib-bepress-aws-west
dc.identifier.submissionpath kin_pubs/35
dc.identifier.uri https://dr.lib.iastate.edu/handle/20.500.12876/52517
dc.language.iso en
dc.source.bitstream archive/lib.dr.iastate.edu/kin_pubs/35/2016_MeyerJ_cc_Meeting_physical_activity_recommendations_may_be_protective_against.pdf|||Fri Jan 14 23:44:14 UTC 2022
dc.source.uri 10.1016/j.dadm.2016.03.005
dc.subject.disciplines Biomechanics
dc.subject.disciplines Exercise Science
dc.subject.disciplines Expeditionary Education
dc.subject.disciplines Kinesiology
dc.subject.disciplines Motor Control
dc.subject.disciplines Psychology of Movement
dc.subject.keywords APOE ε4
dc.subject.keywords Alzheimer's disease
dc.subject.keywords Dementia
dc.subject.keywords Exercise
dc.subject.keywords Family history
dc.subject.keywords Neuroimaging
dc.title Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease.
dc.type article
dc.type.genre article
dspace.entity.type Publication
relation.isAuthorOfPublication 6d25a191-dd56-4965-a726-6dfe139e771a
relation.isOrgUnitOfPublication f7b0f2ca-8e43-4084-8a10-75f62e5199dd
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