The Genetic Immunodeficiency Disease, Leukocyte Adhesion Deficiency, in Humans, Dogs, Cattle, and Mice
dc.contributor.author | Gu, Yu-chen | |
dc.contributor.author | Bauer, Thomas | |
dc.contributor.author | Ackermann, Mark | |
dc.contributor.author | Ackermann, Mark | |
dc.contributor.author | Smith, C. | |
dc.contributor.author | Kehrli, Marcus | |
dc.contributor.author | Starost, Matthew | |
dc.contributor.author | Hickstein, Dennis | |
dc.contributor.department | Veterinary Pathology | |
dc.date | 2018-02-13T06:24:10.000 | |
dc.date.accessioned | 2020-07-07T05:15:49Z | |
dc.date.available | 2020-07-07T05:15:49Z | |
dc.date.embargo | 2013-02-26 | |
dc.date.issued | 2004-08-01 | |
dc.description.abstract | <p>This review highlights the genotype-phenotype relationship of the genetic immunodeficiency disease leukocyte adhesion deficiency (LAD) in humans, dogs, cattle, and mice, and provides assessment of the opportunities that each animal species provides in the understanding of leukocyte biology and in developing new therapeutic approaches to LAD in humans. This comparison is important since animal models of genetic diseases in humans provide the opportunity to test new therapeutic approaches in an appropriate, disease-specific model. The success of this approach is dependent on the relationship of the phenotype in the animal to the phenotype of the disease in humans.</p> | |
dc.description.comments | <p>This article is from C<em>omparative Medicine </em>54, no. 4 (August 2004): 363–372.</p> | |
dc.format.mimetype | application/pdf | |
dc.identifier | archive/lib.dr.iastate.edu/vpath_pubs/26/ | |
dc.identifier.articleid | 1034 | |
dc.identifier.contextkey | 3790614 | |
dc.identifier.s3bucket | isulib-bepress-aws-west | |
dc.identifier.submissionpath | vpath_pubs/26 | |
dc.identifier.uri | https://dr.lib.iastate.edu/handle/20.500.12876/92449 | |
dc.language.iso | en | |
dc.source.bitstream | archive/lib.dr.iastate.edu/vpath_pubs/26/2004_Gu_GeneticImmunodeficiencyDisease.pdf|||Fri Jan 14 23:00:08 UTC 2022 | |
dc.subject.disciplines | Comparative and Laboratory Animal Medicine | |
dc.subject.disciplines | Veterinary Pathology and Pathobiology | |
dc.title | The Genetic Immunodeficiency Disease, Leukocyte Adhesion Deficiency, in Humans, Dogs, Cattle, and Mice | |
dc.type | article | |
dc.type.genre | article | |
dspace.entity.type | Publication | |
relation.isAuthorOfPublication | 86c1ed73-b60d-48ce-8f35-449bc320a693 | |
relation.isOrgUnitOfPublication | cf38d7e3-b5f8-4859-83e3-ae8fab6a4c5f |
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