A pesticide applicator is required to notify all owners of registered beeyards (apiaries) within a 2-mile radius of the site of application if the pesticide is labeled as "toxic to bees." Notification is required at least 24 hours and no more than 72 hours before the application. This enables beekeepers to move or otherwise protect their bees from harm. This notification is required by the Iowa Administrative Code rule IAC 21-45.31(206).